Michael Dyrynda wrote up a follow up on my homestead tips blog post:

Now that you've setup dnsmasq, you can resolve *.dev to your Homestead machine easily, but you still need that manual step of either configuring a new domain in your Homestead.yaml file or using the servecommand within the virtual machine itself. Whilst neither of these methods take a particularly long time to complete, it's still a few seconds of repetition that can be avoided with some tweaking of your default nginx configuration using wildcard hosts. What we'll be doing, is telling nginx to listen for anything sent to it that isn't explicitly configured and look for the domain name in your (default) /home/vagrant/Code directory.